Dry live vaccine against Brucellosis in cattle from the strain Brucella abortus 75/79-АВ
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Immune response:
The immune response occurs within 21 days after vaccination, lasting at least 1 year.
Storage and transportation conditions:
The vaccine is stored and transported in a dark place at a temperature from 2 to 8°С. It is allowed to transport the vaccine at any sub-zero temperature and temperature up to 20°C for no more than 7 days.
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Purpose:
The vaccine is intended for preventive immunization of cattle against brucellosis in disadvantaged and advantaged brucellosis farms in case of a threat of infection of animals.
Description and characteristics:
In appearance the vaccine looks like a dry amorphous mass of light-gray or light-brown colour, lyophilized in a protective environment. The culture of the vaccinal strain Brucella abortus 75/79-АВ, constituting of brucellas in RS- or SR-form, exhibits apparent antigenic and immunogenic properties.
Method of vaccination:
Before application the vaccine is diluted with a special solvent for dry Brucella vaccines in the amount of 5 cm3 per dose. The vaccine is administered to animals according to the direction for use, subcutaneously in the posterior third of the neck at a dose of 5 cm3, for the first time at the age of 4-6 month, again – after 10 months. Immunization is applied only towards brucellosis seronegative animals. Heifers that were not vaccinated at the age of 4-6 months are vaccinated for the first time 2-3 months before insemination. In brucellosis-free farms fresh cows, boosted or immunized first 2-3 months before insemination, are tested for brucellosis in 1-2 months after the whole herds calving. Revaccination is administered by the epizootic indicators at intervals of not less than one year only to the seronegative animals. Positively and doubtfully-reacting animals identified in the diagnostic serological tests are subjected for slaughter.Immune response:
Production form:
The vaccine is packaged into 2-8 cm3 (the dose is determined after final control, possible range from 2-25 doses) bottles of suitable capacity.Storage and transportation conditions:
Shelf life - 12 months.