Dry live vaccine against Brucellosis in cattle from the strain Brucella abortus № 82

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Purpose:
The vaccine is intended for preventive immunization of cattle and reindeer (maral) against brucellosis in disadvantaged and advantaged brucellosis farms in case of a threat of infection of animals.

Description and characteristics:
In appearance, the vaccine is a dry amorphous mass of a light-brown or light-gray color, readily soluble in water for injection or saline without floc formation and precipitation, lyophilized in a protective environment. The culture of the vaccinal strain Brucella abortus 82, constituting brucellas in SR-form.

Method of vaccination:
Before application, the vaccine should be diluted with “The dilution agent for live dry vaccines against brucellosis in livestock animals” assuming 5 cm3 of the dilution agent for 1 dose of the vaccine for cattle. The vaccine is administered subcutaneously in the area of posterior third of the neck in a volume: for cattle - 5 cm3 and reindeer (maral) – 2.5 cm3.
First time the cattle is vaccinated at the age of 4-6 months, again after 10 months. Immunization is applied only towards brucellosis seronegative animals. Heifers that were not vaccinated at the age of 4-6 months are vaccinated for the first time 2-3 months before insemination. Reindeer are vaccinated starting from the age of 4 months, in June-September, but not later than a month before the rut. Vaccinated and revaccinated animals are tested not earlier than 6 months after administration of the vaccine. In farms where diseased animals have been identified, revaccination is carried out with an interval of 10-14 months after vaccination.

Immune response:

The immune response occurs within 21 days after vaccination, lasting at least 1 year.

Production form:

The vaccine is packaged into 2-8 cm3 (the dose is determined after final control, possible range from 2-25 doses of cattle and 4-50 doses of reindeer (maral) bottles of suitable capacity.

Storage and transportation conditions:

The vaccine is stored and transported in a dark place at a temperature from 2 to 8°С. It is allowed to transport the vaccine at any sub-zero temperature and temperature up to 20°C for no more than 7 days. 

Shelf life - 12 months.


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