Live dry vaccine against brucellosis in livestock animals from the strain Brucella abortus 19
Description and characteristics:
In appearance the vaccine looks like a dry amorphous mass of light-gray or light-brown colour, lyophilized in a protective environment.
The culture of the vaccinal strain Brucella abortus 19, constituting of brucellas in S-form, exhibits apparent antigenic and immunogenic properties.
Method of vaccination:
Before application, the vaccine should be diluted with “The dilution agent for live dry vaccines against brucellosis in livestock animals” assuming 4 cm3 of the dilution agent for 1 dose of the vaccine for cattle. The vaccine should be administered in subcutaneous manner: cattle are inoculated in the back third of the neck in the volume of 4 cm3; sheep and goats are inoculated into hairless site behind the elbow joint in the volume of 2 cm3. Only heifers of 4-6-months old are subject to vaccination. Animals should be vaccinated on a single occasion regardless of epizootic situation in farms in terms of brucellosis. In 15-20 days after the vaccination serological studies are carried out and seronegative animals are vaccinated again. Then, after 15-20 days, repeated researches are done and heifers that had not reacted to brucellosis after the repeated administration of the vaccine are transferred to the feeding group. Using them for reproduction is prohibited. Gimmers and doe kids regardless of epizootic situation in farms in terms of brucellosis are vaccinated at 4-6-months-old or two months before breeding without preliminary research on brucellosis. Animals are revaccinated after 12 months and subsequently annually or once every two years.
The vaccine triggers the immune response in 21 days after vaccination, lasting at least 1 year.
Production form:
The vaccine is packaged into 2-8 cm3 (the dose is determined after final control, possible range from 2-25 doses for cattle or from 4-50 doses for small cattle) bottles of suitable capacity.
Storage and transportation conditions: